Words with just one vowel make an interesting set. Remember, in Spanish one vowel means one vowel sound and also one vowel symbol (a, e, i, o, u).

If you take into account that every Spanish syllable needs at least one vowel sound, and that every word has at least one syllable (obviously), this makes the one-vowel words the simplest words; and, many are very common. Does that mean “important”? You decide that.
# | Grammar words | Translation | # | Non grammar words (no verbs) | Translation | # | Verbs | Translation |
1. | a | to, at, A | 47. | as | ace | 124. | da | gives |
2. | al | to the | 48. | bar | bar (pub) | 125. | dan | they give |
3. | con | with | 49. | be | B | 126. | dar | to give |
4. | de | of, from, D | 50. | cal | lime | 127. | das | you give |
5. | del | of the | 51. | ce | C | 128. | dé | give! |
6. | e | and | 52. | clan | clan | 129. | di | gave |
7. | el | the | 53. | clon | clone | 130. | es | is |
8. | él | he | 54. | col | cabbage | 131. | ha | s/he has |
9. | en | in, on, at | 55. | coz | horse kick | 132. | han | they have |
10. | la | the | 56. | crin | horsehair | 133. | has | you have |
11. | las | the | 57. | crol | crawl | 134. | haz | make! |
12. | le | to him/her/it | 58. | cruz | cross | 135. | he | I have |
13. | les | to you guys/them | 59. | cu | Q | 136. | ir | to go |
14. | lo | him/her/it | 60. | do | do (music) | 137. | pon | put! |
15. | los | the | 61. | dos | two | 138. | sal | get out! |
16. | me | I, me | 62. | fa | fa (music) | 139. | sé | I know |
17. | mi | me | 63. | fax | fax | 140. | ser | to be |
18. | mí | me | 64. | fe | faith | 141. | son | they are |
19. | mis | my | 65. | flan | pudding | 142. | ten | have! |
20. | ni | neither | 66. | flor | flower | 143. | va | goes |
21. | no | not | 67. | folk | folk | 144. | van | they go |
22. | nos | us | 68. | gas | gas | 145. | vas | you go |
23. | o | or, either, O | 69. | ge | G | 146. | ve | s/he sees |
24. | os | to you guys (Spain) | 70. | gel | gel | 147. | vé | go! |
25. | por | for | 71. | gen | gene | 148. | ven | come! |
26. | que | that | 72. | gol | goal | 149. | ver | to see |
27. | qué | what | 73. | gong | gong | 150. | ves | you see |
28. | se | him/her/it/themselves | 74. | gran | big | 151. | vi | I saw |
29. | si | if | 75. | gris | grey | |||
30. | sí | yes | 76. | haz | make!, beam of light | |||
31. | sin | without | 77. | hoz | sickle | |||
32. | su | his/her/its/their | 78. | i | i | |||
33. | sus | his/her/its/their | 79. | ka | K | |||
34. | tal | such | 80. | kril | krill | |||
35. | tan | so | 81. | luz | light | |||
36. | te | you, T | 82. | mal | wrong | |||
37. | ti | you | 83. | mar | sea | |||
38. | tras | after | 84. | más | plus | |||
39. | tu | your | 85. | mes | month | |||
40. | tú | you | 86. | mil | one thousand | |||
41. | u | or, U | 87. | mol | mole | |||
42. | un | a | 88. | mus | mus | |||
43. | vos | you (Argent.) | 89. | ñu | gnu | |||
44. | y | and | 90. | pan | bread | |||
45. | ya | already | 91. | par | pair | |||
46 | yo | I | 92. | paz | peace | |||
93. | pe | P | ||||||
94. | pez | fish | ||||||
95. | pi | pi | ||||||
96. | pin | pin | ||||||
97. | plan | plan | ||||||
98. | plus | plus | ||||||
99. | pop | pop | ||||||
100. | pus | pus | ||||||
101. | re | re (music) | ||||||
102. | res | beef | ||||||
103. | rol | role | ||||||
104. | ron | rum | ||||||
105. | sal | salt | ||||||
106. | san | saint | ||||||
107. | sed | thirst | ||||||
108. | sol | sun | ||||||
109. | sur | south | ||||||
110. | té | tea | ||||||
111. | test | test | ||||||
112. | tez | face skin | ||||||
113. | tic | tic | ||||||
114. | tos | cough | ||||||
115. | tren | train | ||||||
116. | tres | three | ||||||
117. | vals | waltz | ||||||
118. | vez | time | ||||||
119. | vil | vile | ||||||
120. | voz | voice | ||||||
121. | ye | Y | ||||||
122. | zar | czar | ||||||
123. | zen | zen | ||||||
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